Transmembrane serine/threonine kinase forming with the TGF-beta
type I serine/threonine kinase receptor, TGFBR1, the non promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2
and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from
the cell surface to the cytoplasm and is thus regul..
£190.00
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylat..
£210.00
Metalloproteinase inhibitor that functions by forming
one to one complexes with target metalloproteinases, such as collagenases, and
irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts
on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.
Does n..
£170.00
TIMP2 encoded by Timp2 gene are natural inhibitors of the matrix metalloproteinases (MMP), a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, it has a unique role among TIMP family members in its ability to directl..
£290.00
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumour cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,..
£350.00
The TNFAIP2 gene was identified as a gene whose expression can be induced by the tumour necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor..
£300.00
This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multi..
£320.00
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulphate and heparin. NRP1/N..
£175.00
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot g..
£350.00
New
Cy3 (Cyanine 3) is a water-soluble cyanine dye, which is brighter, more stable and weaker than other fluorophores, so it is widely used in biomolecular labelling, fluorescence imaging and other fluorescence biological analysis. Cy3-conjugated Donkey Anti-Goat IgG (H+L) (Cy3 conjugated Donkey An..
£150.00
New
Cy3 (Cyanine 3) is a water-soluble cyanine dye, which is brighter, more stable and weaker than other fluorophores, so it is widely used in biomolecular labelling, fluorescence imaging and other fluorescence biological analysis. Cy3-conjugated Donkey Anti-Mouse IgG (H+L) (Cy3 conjugated Donkey A..
£150.00
New
Cy3 (Cyanine 3) is a water-soluble cyanine dye, which is brighter, more stable and weaker than other fluorophores, so it is widely used in biomolecular labelling, fluorescence imaging and other fluorescence biological analysis. Cy3-labeled Donkey Anti-Rabbit IgG (H+L) (Cy3 conjugated Donkey Ant..
£150.00