The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Antibodies
Application
Western Blot
Application Note
For research purposes only. Not for use in humans.
Dilution
1:600 - 1:1000
Host
Rabbit Polyclonal
Isotype
IgG
Molecular Weight
175 kDa
Positive Tissue
HepG2,A549,A431,Hacat,Hct116
Purity
Affinity purification
Species
Human
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
