The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Antibodies
Application
Immunofluorescence
Application Note
For research purposes only. Not for use in humans.
Dilution
1:500 - 1:1000
Host
Rabbit
Immunogen
Recombinant protein corresponding to Mouse CD8 beta
Isotype
IgG
Positive Tissue
lung cancer, colon, spleen, thymus
Purity
Affinity purification
Species
Human, Rat
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
