Anti - TIMP1 Mouse mAb
Metalloproteinase inhibitor that functions by forming
one to one complexes with target metalloproteinases, such as collagenases, and
irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts
on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.
Does not act on MMP14. Also functions as a growth factor that regulates cell
differentiation, migration and cell death and activates cellular signalling
cascades via CD63 and ITGB1. Plays a role in integrin signalling. Mediates
erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating
the growth and differentiation of only human and murine erythroid progenitors.
Antibodies | |
Application | Immunohistochemistry, Immunofluorescence |
Application Note | For research purposes only. Not for use in humans. |
Immunogen | Synthesized peptide derived from human TIMP1 |
Purity | Affinity Purified |
Source | Mouse |
Species | Human |
Proteins Full Name | Metalloproteinase inhibitor 1 |
- Stock: In Stock
- Model: SBA048
£170.00