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Anti - TIMP1 Mouse mAb

Anti - TIMP1 Mouse mAb
Anti - TIMP1 Mouse mAb
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signalling cascades via CD63 and ITGB1. Plays a role in integrin signalling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. 
Antibodies
Application Immunohistochemistry, Immunofluorescence
Application Note For research purposes only. Not for use in humans.
Immunogen Synthesized peptide derived from human TIMP1
Purity Affinity Purified
Source Mouse
Species Human
Proteins Full Name Metalloproteinase inhibitor 1
  • Stock: In Stock
  • Model: SBA048
£170.00

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