Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival and chemotaxis. Mutations in PDGFRA gene have been associated with idiopathic hyper-eosinophilic syndrome, somatic and familial gastrointestinal stromal tumours, and a variety of other cancers.
Antibodies
Application
Western Blot
Application Note
For research purposes only. Not for use in humans.
Dilution
1:500 - 1:1000
Host
Rabbit Polyclonal
Immunogen
Recombinant protein corresponding to Mouse PDGFR alpha
Isotype
IgG
Molecular Weight
190 kDa
Positive Tissue
heart, embryo
Purity
Affinity purification
Species
Mouse, Rat
Synonyms
PDGF-R-alpha, PDGFR alpha, CD140a, Pdgfra, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor
