Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signalling is modulated by the formation of heterodimers with PDGFA.
Antibodies
Application
Western Blot, Immunohistochemistry/Immunofluorescence
Application Note
For research purposes only. Not for use in humans.
Host
Rabbit Polyclonal
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PDGFB
