May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Antibodies
Application
Western Blot, Immunohistochemistry, Immunofluorescence
Application Note
For research purposes only. Not for use in humans.
Dilution
[WB: 1:500 - 1:1000] [IHC, IF: 1:500 - 1:2000]
Host
Rabbit Polyclonal
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse MMP9
Isotype
IgG
Positive Tissue
Liver, Spleen
Purity
Affinity purification
Species
Mouse, Rat
Subcellular Location
Secreted
Synonyms
MMP9, CLG4B, GELB, MANDP2, MMP-9,92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B, matrix metallopeptidase 9
