Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodelling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Antibodies
Application
Immunohistochemistry
Application Note
For research purposes only. Not for use in humans.
Dilution
1:2400 - 1:4800
Host
Rabbit Polyclonal
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse MMP10
Positive Tissue
Cholangiocarcinoma, Lung Cancer
Purity
Affinity purification
Species
Human
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
