CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 has been shown to interact with CCL4, and attracts macrophages, monocytes and neutrophils. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumour necrosis factor or recombinant human interleukin-1.
Antibodies
Application
Immunohistochemistry, Immunofluorescence
Application Note
For research purposes only. Not for use in humans.
Dilution
1:200 - 1:800
Host
Rabbit Polyclonal
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse CCL3
