Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
Antibodies
Application
Immunohistochemistry, Immunofluorescence
Application Note
For research purposes only. Not for use in humans.
Dilution
[IHC: 1:500 - 1:3000] [IF: 1:500 - 1:1000]
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse M-CSF Receptor
