LBP (lipopolysaccharide-binding protein) is an acute-phase protein, predominantly synthesized by hepatocytes. It is present in normal serum at concentrations of 5 to 10 μg/ml, rising up to 200 μg/ml 24 h after induction of an acute-phase response. LBP binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS.
Antibodies
Application
Western Blot
Application Note
For research purposes only. Not for use in humans.
Host
Rabbit Polyclonal
Immunogen
Recombinant protein corresponding to Mouse LBP
Isotype
IgG
Molecular Weight
67 kDa
Positive Tissue
liver, ovary, thymus
Purity
Affinity purification
Species
Mouse, Rat
Synonyms
LBP, Bpifd2, LPS binding protein, Ly88, BPI fold containing family D, member 2
