FGF6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF6 is expressed in leukaemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. The FGF6 gene displays oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
Antibodies
Application
Western Blot
Application Note
For research purposes only. Not for use in humans.
Dilution
1:500 - 1:1000
Host
Rabbit Polyclonal
Immunogen
Recombinant protein corresponding to Mouse FGF6
Isotype
IgG
Molecular Weight
23 kDa
Positive Tissue
brain, heart
Purity
Affinity purification
Species
Mouse
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
