Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion (1, 2). Has semicarbazide-sensitive (SSAO) monoamine oxidase activity (3, 4). May play a role in adipogenesis. Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. The soluble form of VAP-1 is released into the circulation mainly from vascular endothelial cells. Over- and under-expression of sVAP-1 result in alterations of the reported reaction product levels, which are involved in the pathogenesis of multiple human diseases (5, 6). Product is shipped either on dry or wet ice. Upon receipt, store at -20°C to -70°C
Antibodies
Amino Acids
29-763
Application Note
For research purposes only. Not for use in humans.
Endotoxins
Less than 0.1 ng/µg (1 IEU/µg), as measured by LAL method.
Formulations
PBS 20% Glycerol
Grade & Purity
>95% as estimated by SDS-PAGE stained with Instant Blue Stain
(Expedeon)
Molecular Weight
83 kDa
Protein ID
Q16853
Source
HEK293
Species
Human
Stability
At least 12 months at -20°C to -70°C and at least 1 month at 2°C to 8°C.
Storage
The protein should be stored at -20°C to -70°C preferably in small aliquots to
avoid repeated freeze-thaw cycles
