The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumour growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
Antibodies
Application
Immunohistochemistry
Application Note
For research purposes only. Not for use in humans.
Dilution
1:400 - 1:8000
Host
Rabbit Polyclonal
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse FGF10
Isotype
IgG
Positive Tissue
Colon, small intestine, colonitis
Purity
Affinity purification
Species
Mouse, Rat
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles
Subcellular Location
Secreted
Synonyms
Keratinocyte growth factor 2, FGF-10, Fgf10, KGF 2, Produced by fibroblasts of urinary bladder lamina propria
