Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix(ECM) in normal physiological processes, such as embryonic development, reproduction, and tissue remodelling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
Antibodies
Application
Western Blot
Application Note
For research purposes only. Not for use in humans.
Dilution
1:500 - 1:1000
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse MMP2
