TIMP2 encoded by Timp2 gene are natural inhibitors of the matrix metalloproteinases (MMP), a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, it has a unique role among TIMP family members in its ability to directl..
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumour cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,..
The TNFAIP2 gene was identified as a gene whose expression can be induced by the tumour necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor..
This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multi..
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulphate and heparin. NRP1/N..
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot g..
A 96 well black plate with an optically clear flat bottom and clear lidOpaque walls prevent well - to - well crosstalk and auto-fluorescenceCompatible with standart fluorescence microplate readers..
Our individually wrapped plates have been sterilised and are pyrogen - free. All culture - treated plates are manufactured under cGMP conditions ensuring reproducibility and healthy cell growth.6-well plate: Consists of 6 individual wells arranged in a 2x3 configuration. Each well typically has a vo..
Cell strainers are applicable to the preparation of samples for flow cytometric analysis and single cell suspension of blood cells, the rapid separation of primary cultured cells and primary cells from tissues, etc., and the pre filtration of cells with a diameter greater than 40 μm particle s..
The centrifugal filter is a disposable filtration device that combines centrifugal force and ultrafiltration technology to provide reliable data for concentration, desalination and buffer exchange of protein samples in biological experiments. Compared with chromatography and dialysis, the ultra..
All centrifuge tubes made from polypropylene are sterile, enzyme - free, pyrogen - free, and are constructed to withstand centrifugal forces of up to 17500g. They are autoclavable and can withstand cryogenic conditions. Quantity Options:1 rack (50 centrifuge tubes) - £15.00; 1 carton (10 r..
All centrifuge tubes made from polypropylene are sterile, enzyme - free, pyrogen - free, and are constructed to withstand centrifugal forces of up to 17500g.. They are autoclavable and can withstand cryogenic conditions. Quantity Options:1 rack (25 centrifuge tubes) - £9.00; 1 carton (10 r..